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union-jack-english-flag.png French version  

MASTER of Cancer Biology

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Master of Cancer Biology second year offers a deepening in the field of oncology by offering several internships and the opportunity to obtain Level 1 animal experimentation accreditation.

 

Agnès BERNET

      Head of Master of Cancer Biology

   agnes.bernet@lyon.unicancer.fr

 


→ First semester teaching units (30 ECTS)

 

 

  • Cancer research internship - 21 ECTS 
    The Apogée code for internship agreements is: IPH2136M.

                ✉ Responsible for teaching unit :  Joanna FOMBONNE (joanna.fombonne@lyon.unicancer.fr)

                                                             Olivier MEURETTE (olivier.meurette@lyon.unicancer.fr)

                 ✎ Evaluation methods:  Review 25 000 characters max | Oral presentation (10 min + 10 min questions) | Supervisor appreciation

 

  •  Scientific literature news - 6 ECTS

The objective of this teaching unit is to present to students the latest major advances in the field of basic and applied oncology researches.

The courses will be given in the form of a dozen conferences by French or foreign researchers, invited by the heads of the teaching unit. Each theme will be covered in half a day and students will be given a high point  for a constructive exchange with the speakers. Each conference will be preceded by a tutorial classes during which the speaker's most recent article will be analyzed in detail.

The end of this teaching unit will be through the organization of a symposium during which students will present an article selected by the teaching unit responsible for the conference.

Students will be assessed both on their exchange with the speakers and on the presentation of articles as well as on a paper on the research perspectives of the papers presented.


                  ✉ Responsible for teaching unit :  Olivier MEURETTE (olivier.meurette@lyon.unicancer.fr)

                                                             Stéphanie SENTIE (stephanie.sentis@lyon.unicancer.fr)

                   

                 ⊕ Time Distribution : 20h Lecture | 40h DG 

                 ❝❞ Languages : French and English

                 ✎ Evaluation methods : continuous monitoring - 2 oral presentations + 1 oral presentation for the Symposium at the end of the teaching unit.

 

      • English for professional communication - level 2 - 3 ECTS  
Teaching unit which favors scientific English, training in oral expression, the layout of a symposium poster, etc.

                 ✉ Responsible for the teaching unit : Joann PIGAT (joann.pigat@univ-lyon1.fr )

                 ⊕ Time distribution : 30h DG 

                 ❝❞ Languages : English

                 ✎ Evaluation methods: continuous monitoring (100%)

 

 

→ Second semester teaching units (30 ECTS)

 

    • PhD preparatory internship  - 24 ECTS 
      The Apogée code for internship agreements is: IPH2138M.

                   ✉ Responsible for teaching unit : Agnès BERNET (agnes.bernet@lyon.unicancer.fr)

                                                            Ulrich VALCOURT (ulrich.valcourt@lyon.unicancer.fr)

                    ✎ Evaluation methods :  Internship report like scientific publication |  Oral presentation 10 min + 10 questions 

 

  • Optional teaching unit - 6 ECTS

 Choose 1 teaching unit

    • Environmental factors and carcinogenesis - 6 ECTS

Study of environmental, occupational and nutritional factors and exploration of associated molecular mechanisms. The teaching unit address the fundamentals between environment and cancer, the introduction to health / environment, the criteria of causality and classification of carcinogenic substances as well as the different methods for the environmental factors study.

                  ✉ Responsible for teaching unit :   Béatrice FERVERS (beatrice.fervers@lyon.unicancer.fr)

                  ⊕ Time distribution : 44h Lecture| 16h G

                  ❝❞ Languages :  French and english

                  ✎ Evaluation methods : Lecture : written exam (75%) | DG : oral (25%)

 

                    or 2 teaching units (3 ECTS) among :

 

  • Aging and Cell Death - 3 ECTS

 Biology of cell death: necrosis, necroptosis, apoptosis and autophagy and their relationship to aging Cellular senescence: molecular mechanisms of control and escaping. Cellular aging and damage to molecules: reactive oxygen species, proteins, nucleic acids Cellular aging and metabolism: theories of caloric restriction, metabolic signalling pathways Physiopathology of aging: organisms longevity, aging diseases and neurodegenerative diseases

                  ✉ Responsible for teaching unit  : Carole KRETZ (Carole.Kretz@univ-lyon1.fr)

                  ⊕ Time distribution : 13h Lecture | 5h DG

                  ❝❞ Languages : English and French

                  ✎ Evaluation methods : Oral presentation (75%) | continuous monitoring (25%)

 

  • Biostatistics et Bioinformatics - 3 ECTS

6 hours of courses in which the main biostatistical tools are discussed, 24 hours of practical work focused on the search for sequence homologies (blast) of analysis, the construction of phylogenetic trees, the putting into experimental situations, statistics design, etc.

                  ✉ Responsible for teaching unit : Raquel TAVARES (Raquel.Tavares@univ-lyon1.fr)

                  ⊕ Time distribution : 6h Lecture | 24h Laboratory

                  ❝❞ Languages :  French

                  ✎ Evaluation methods : Final exam

 

  • Level 1 animal experimentation accreditation (CPUAFS) - 3 ECTS

This training will take place at the veterinary school of Lyon (VetAgro Sup campus - Marcy l'étoile) The goal is to allow students who wish to validate the Level 1 animal experimentation by continuing the study of animal models started in the first year of master of oncology.

Spontaneous models in experimental oncology: oncogenesis, specificities related to the domestic animal, specificities of the clinical veterinary oncology framework, ethical regulation, design and implementation of pre-clinical and clinical tests in animals, animal samples and tumor banks and quality system.

 

                  ✉ Responsible for teaching unit :   Delphine GREZEL (delphine.greze@vetagro-sup.fr)

                  ⊕ Time distribution : 15h lecture |15 h DG

                  ❝❞ Languages :  French           

                  ✎ Evaluation methods : Final written exam (100%)

 

  • Focused destruction of cancer - 3 ECTS
Sensitization to the recent development of complementary and alternative techniques to pharmacological treatments for cancer (rapid introduction to surgery) / targeted destruction by non-ionizing physical means (ultrasound, radiofrequency, laser, microwaves) / focused destruction by radiotherapy).
 

                  ✉ Responsible for teaching unit: Frédéric PADILLA ( frederic.pad@gmail.com)

                                                           Michel RIVOIRE (michel.rivoire@lyon.unicancer.fr)

                  ⊕ Time distribution : 20 h Lecture  |  5h DG

                  ❝❞ Languages : French. Courses material in english

                  ✎ Evaluation methods : Final written exam (100%)

  

  • Drug Delivery + additional memory- 3 ECTS

The objective of this course is to introduce students to the use of nanotechnology for the development of new types of contrast agents and drugs that specifically target cancer cells for diagnostic and therapy purposes (theranostics).

The course is divided into four parts:

1- General introduction, principle and hopes,
2- How to design nanoparticles for imaging, vectorization and drug delivery?
3- Medical imaging.
4- Vectorization and therapy.

                  ✉ Responsible for teaching unit : Charlotte Rivière (charlotte.riviere@lpmcn.univ-lyon1.fr)

                  ⊕ Time distribution: 10hDG

                  ❝❞ Languages : English

                  ✎ Evaluation methods : Mid-term evaluation and oral presentation of scientific publication

   

  • Health economy and cancer - 3 ECTS

Different topics will be covered: Health Systems (HMS), Health Expenditure (NM) Health Expenditure Control, Health Care Supply (NM and HMS), Health Professionals (NM), Health Institutions (HMS), and an introduction to the medico-economic evaluation

                 ✉ Responsible for teaching unit :   Nora MOUMJID (nora.moumjid@univ-lyon1.fr)

                                                           Carole Siani (carole.siani@univ-lyon1.fr)

                                                             and Hans‐Martin SPATH (Hans-Martin.Spath@adm.univ-lyon1.fr)

 

                ⊕ Time distribution : 24h Lecture | 6h DG 

                 ❝❞ Languages : French

                 ✎ Evaluation methods : Written final exam - Courses (66.67%) | Oral presentation - Practical Work (33.33%)

 

  • Emerging concepts in functional genomics - 3 ECTS
It is a teaching unit of openness and questioning around recent advances in genetics or functional genomics and their applications to the understanding of cell biology. The teaching unit consists of a series of conferences and courses given by researchers and teacher-researchers who have contributed to the emergence of new concepts and concepts in these scientific fields. It aims to stimulate students' thinking skills by allowing them to access the latest advances in the field of genetics and cell biology. It aims to build a research project around one of the topics addressed by the conferences. It requires students a personal work around a mini research project, "tutored" by teachers of the teaching unit, to train them in the scientific process.
The themes are renewed each year by a steering committee made up of different teachers from the teaching unit, according to the evolution of knowledge in the field of functional genomics, molecular genetics and cell physiology.

                  ✉ Responsible for teaching unit :   Jérome LAMARTINE  ( jerome.lamartine@univ-lyon1.fr)

                  ⊕ Time distribution : 10h Lectures | 8h DG

                  ❝❞ Languages : English

                  ✎ Evaluation Methods :  preparation of a research project related to the theme of the course (80%) + note of participation of students in scientific discussions (20%)

 

 

  • Immunology & Cancer - 3 ECTS
This teaching unit builds on students' basic immunology knowledge to develop fundamental research concepts in immunology that have applications in clinical and pharmaceutical research in the field of oncology. The topics will be:

 

  • anti-tumor immune response and its manipulation

Action mechanisms of carcinogens of infectious origin; the "multi-hit-multi-step" or step progression of cancerization; the antigenic profile of the tumor cells; molecular analysis of the tumor microenvironment; Functional alterations of immune system cells infiltrating tumors

  • Immune system cancers

Panorama and specificity within cancers; analysis of the immune response after immunotherapy; tumor escape mechanisms; monoclonal antibodies in cancer immunotherapy; Hematopoietic stem cell transplantation as a model for immunotherapy

  • the protection of patients immunosuppressed by treatments or following an infection.

Cytokine action mechanisms capable of restoring immune functions during chemo or radiotherapy; concept of secondary cancer and state of research on the parameters useful for monitoring the occurrence of an infection or cancer on models of studies relating to organ or blood donation, patients infected by HIV or HCV, to patients immunosuppressed by treatment following a transplant or primary cancer.

 

                  ✉ Responsible for teaching unit :   Christine DELPRAT  (christine.delprat@univ-lyon1.fr)

                  ⊕ Time distribution : 18h Lecture

                  ❝❞ Languages : English

                  ✎ Evaluation methods : Courses : final written exam (50%) + oral presentation (50%)

 

  •  Metastasis, Migration et EMT- 3 ECTS
Acquisition of the most recent concepts of the metastatic dissemination process, knowledge of colonization mechanisms at molecular and cellular levels, early detection method, notion of niche and dormancy and targeted therapies        

 ✉ Responsible for teaching unit :  Chantal Diaz (chantal.diaz@univ-lyon1.fr)

                 ⊕ Time distribution : 20h Lecture | 10h DG 

                 ❝❞ Languages : French

                 ✎ Evaluation methods : Lecture: written exam (100%)

 

  • Think cancer in the light of the patient himself - 3 ECTS

Bring humanities and social sciences into the scientific training as a complement. Put into action the national guidelines of the CNIB. Contribute to a perspective of the Descartes epistemology from which science comes to understand its strengths and limitations

                  ✉ Responsible for teaching unit :  Romain PARENT  (romain.parent@inserm.fr)

                  ⊕ Time distribution : 25 h DG

                  ❝❞ Languages :  French           

                  ✎ Evaluation methods : Dissertation (10 pages) deadline : june

 

  • Pharmaceutical industries strategy and technologies MED- 3 ECTS

Teaching unit from IAE School. Scheduled between November and February

                  ✉ Responsible for teaching unit: Corinne Montoya

                  ⊕ Time distribution : 46h lecture

                  ❝❞ Languages : Not mentionned by the responsible               

                  ✎ Evaluation methods : Not mentionned by the responsible   

 

  • Tissue and cell engineering + additional memory- 3 ECTS

      Lecture part
A) Phenotypic and Mechanical characterization of cells and tissues  – force, adhesion and motility studies - microsystems for cell culture, diagnosis, drug screening…  : 8 hours 
B) Biomaterials and scaffolds able to finely tune various cell responses  : 6 hours

    Practical part
C) Basics of Image Analysis 
-3 theoretical courses with examples on a free software Image J -3 courses for developing a project in tandem : tracking endothelial cells on patterned surfaces. 

 

                  ✉ Responsible for teaching unit :   Jean-Paul RIEU (jean-paul.rieu@univ-lyon1.fr)

                  ⊕ Time distribution : 10h Lecture | 12h DG

                 ❝❞ Language : English

                 ✎ Evaluation methods : Lecture : Bibliographic assay (50%) + Projet Report (50%)