French versionMASTER of Therapeutic innovations in oncology
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MASTER of Therapeutic innovations in oncology offers an in-depth study in the field of oncology by offering several internships and the opportunity to obtain Level 1 animal experimentation accred |
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Hicem MERTANI Head of Master of Therapeutic Innovations in Oncology hichem.mertani@univ-lyon1.fr |
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Charles DUMONTET
Head of Master of Therapeutic Innovations in Oncology charles.dumontet@chu-lyon.fr |
→ First semester teaching unit (30 ECTS)
- Cancer research internship - 21 ECTS
The Apogée code for internship agreements is: IPH2136M.
✉ Responsible for teaching unit : Hichem MERTANI (hichem.mertani@univ-lyon1.fr)
✎ Evaluation methods: Internship report and review + supervisor evaluation / English
- Preclinical development, clinical trial and Pharmaco-Toxico - 6 ECTS
Education divided into 3 major parts: design of anticancer drugs and pharmacological and resistance mechanism; pharmaco-toxicology in the development of an anticancer drug; pre-clinical and clinical trials of the drug in oncology.
✉ Responsible for teaching unit : Lea PAYEN (lea.payen@univ-lyon1.fr)
⊕ Time Distribution : 40h Lecture | 25h DG
❝❞ Languages : French. Courses material in english
✎ Evaluation methods : Contineous monitoring, oral presentation and final exam
- English for professional communication - level 2 - 3 ECTS
Teaching unit which favors scientific English, training in oral expression, the layout of a symposium poster, etc.
✉ Responsible for the teaching unit : Joann PIGAT (joann.pigat@univ-lyon1.fr )
⊕ Time distribution : 30h DG
❝❞ Languages : English
✎ Evaluation methods: continuous monitoring (100%)
→ Second semester teaching units (30 ECTS)
- Academic research internship or company internship - 24 ECTS
The Apogée code for internship agreements is: IPH2146M
✉ Responsible for teaching unit : Charles DUMONTET (charles.dumontet@univ-lyon1.fr)
✎ Evaluation Methods : Internship report (40%), oral presentation (40%), Supervisor evaluation (20%)- English
- Translational research from animal to human - 3 ECTS
The topics covered in this course are:
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Spontaneous cancers in animals: haematological malignancies, skin tumors (particularly melanoma squamous cell carcinoma), breast tumors, Sarcomas, other tumors (prostate tumors glioma ...)
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Application to veterinary medicine: animal translational research / clinical trials: development of the veterinary drug: potential and limits regulatory framework
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The application to humans: translational research animal-man: kinships and differences in epidemiology, clinical and therapeutic
✉ Responsible for teaching unit Frédérique PONCE (frederique.ponce@vetagro-sup.fr)
⊕ Time distribution : 13h Lecture | 15h DG
❝❞ Languages : French. Courses material in english
✎ Evaluation methods : Review, continuous monitoring and final exam
- Optional teaching units - 3 ECTS
Choose 1 teaching unit
- Biostatistics et Bioinformatics - 3 ECTS
6 hours of courses in which the main biostatistical tools are discussed, 24 hours of practical work focused on the search for sequence homologies (blast) of analysis, the construction of phylogenetic trees, the putting into experimental situations, statistics design, etc.
✉ Responsible for teaching unit : Raquel TAVARES (Raquel.Tavares@univ-lyon1.fr)
⊕ Time distribution : 6h Lecture | 24h Laboratory
❝❞ Languages : French
✎ Evaluation methods : Final exam
- Level 1 animal experimentation accreditation (CPUAFS) - 3 ECTS
This training will take place at the veterinary school of Lyon (VetAgro Sup campus - Marcy l'étoile) The goal is to allow students who wish to validate the Level 1 animal experimentation by continuing the study of animal models started in the first year of master of oncology.
Spontaneous models in experimental oncology: oncogenesis, specificities related to the domestic animal, specificities of the clinical veterinary oncology framework, ethical regulation, design and implementation of pre-clinical and clinical tests in animals, animal samples and tumor banks and quality system.
✉ Responsible for teaching unit : Delphine GREZEL (delphine.greze@vetagro-sup.fr)
⊕ Time distribution : 15h Lecture | 15 h DG
❝❞ Languages : French
✎ Evaluation methods : Final written exam (100%)
- Focused destruction of cancer - 3 ECTS
✉ Responsible for teaching unit: Frédéric PADILLA ( frederic.pad@gmail.com)
Michel RIVOIRE (michel.rivoire@lyon.unicancer.fr)
⊕ Time distribution : 20 h Lecture | 5h DG
❝❞ Languages : French. Courses material in english
✎ Evaluation methods : Final written exam (100%)
- Drug Delivery + additional memory- 3 ECTS
The objective of this course is to introduce students to the use of nanotechnology for the development of new types of contrast agents and drugs that specifically target cancer cells for diagnostic and therapy purposes (theranostics).
The course is divided into four parts:
1- General introduction, principle and hopes,
2- How to design nanoparticles for imaging, vectorization and drug delivery?
3- Medical imaging.
4- Vectorization and therapy.
✉ Responsible for teaching unit : Charlotte Rivière (charlotte.riviere@lpmcn.univ-lyon1.fr)
⊕ Time distribution: 10h DG
❝❞ Languages : English
✎ Evaluation methods : Mid-term evaluation and oral presentation of scientific publication
- Health economy and cancer - 3 ECTS
Different topics will be covered: Health Systems (HMS), Health Expenditure (NM) Health Expenditure Control, Health Care Supply (NM and HMS), Health Professionals (NM), Health Institutions (HMS), and an introduction to the medico-economic evaluation
✉ Responsible for teaching unit : Nora MOUMJID (nora.moumjid@univ-lyon1.fr)
Carole Siani (carole.siani@univ-lyon1.fr)
and Hans‐Martin SPATH (Hans-Martin.Spath@adm.univ-lyon1.fr)
⊕ Time distribution : 24h Lecture | 6h DG
❝❞ Languages : French
✎ Evaluation methods : Final written exam - Courses (66.67%) | Oral presentation - Practical Work (33.33%)
- Innovation and industrial property - 3 ECTS
The speakers all have IP expertise and come from the academic world of research, the National Institute of Industrial Property (INPI) and "industrial property advice" firms.
The teaching consists of six courses:
- CM 1 Inaugural conference on the intellectual property (1 hour).
- CM 2 Patents A to Z (4 hours).
- CM 3 Worldwide Patent Databases (2 hours).
- CM 4 Patent infringement and litigation (3 hours).
- CM 5 Counterfeiting (2 hours).
-CM 6 Experience feedback on IP (2 hours).
The courses are reinforced by two sessions of TD, in computer room, to carry out a concrete work around the searchable databases in network (Internet):
- TD 1 Online access to patents (2 hours).
- TD 2 Patent case study (2 hours).
✉ Responsible for teaching unit: Marc LE BORGNE (marc.le-borgne@univ-lyon1.fr)
⊕ Time distribution : 14h Lecture | 4h DG
❝❞ Languages : French
✎ Evaluation Methods : Final written exam
- Metastasis, Migration et EMT- 3 ECTS
✉ Responsible for teaching unit : Chantal Diaz (chantal.diaz@univ-lyon1.fr)
⊕ Time distribution : 20h Lecture | 10h DG
❝❞ Languages : French
✎ Evaluation methods : Lecture: written exam (100%)
- Think cancer in the light of the patient himself - 3 ECTS
Bring humanities and social sciences into the scientific training as a complement. Put into action the national guidelines of the CNIB. Contribute to a perspective of the Descartes epistemology from which science comes to understand its strengths and limitations
✉ Responsible for teaching unit : Romain PARENT (romain.parent@inserm.fr)
⊕ Time distribution : 25 h DG
❝❞ Languages : French
✎ Evaluation methods : Dissertation (10 pages) deadline : june
- Targeted therrapies and smal molecules- 3 ECTS
The aim of the teaching unit is to gain knowledge on the "small molecule" side of kinase inhibitors (ATP-competitive, allosteric modulators, inhibitors of protein-protein interactions).
The curriculum is articulated around seven interventions:
- CM 1 Conference in the field of kinase inhibitors (1 hour) "Targeting cancer with small molecule kinase inhibitors"
- CM 2 "Design and Kinase Inhibitor Chemistry" (3 hours)
- CM 3 Structure-Based Drug Design (2 hours)
- CM 4 Ligand-Based Drug Design (2 hours)
- CM 5 Physicochemical properties and ADMET parameters of kinase inhibitors (2 hours)
- CM 6 Specificities and mechanisms of action of kinase inhibitors (2 hours)
- CM 7 Vectorization of kinase inhibitors (2 hours)
The courses are complemented by two TD sessions:
- TD 1 Case Study 1 (2 hours)
- TD 2 Case Study 2 (2 hours)
✉ Responsible for teaching unit: Marc LE BORGNE (marc.le-borgne@univ-lyon1.fr)
⊕ Time distribution : 18h Lecture
❝❞ Languages : Not specified
✎ Evaluation Methods : Not specified
- Tissue and cell engineering + mémoire complémentaire- 3 ECTS
Lecture part
A) Phenotypic and Mechanical characterization of cells and tissues – force, adhesion and motility studies - microsystems for cell culture, diagnosis, drug screening… : 8 hours
B) Biomaterials and scaffolds able to finely tune various cell responses : 6 hours
Practical part
C) Basics of Image Analysis
-3 theoretical courses with examples on a free software Image J -3 courses for developing a project in tandem : tracking endothelial cells on patterned surfaces.
✉ Responsible for teaching unit : Jean-Paul RIEU (jean-paul.rieu@univ-lyon1.fr)
⊕ Time distribution: 10h Lecture
❝❞ Languages : English
✎ Evaluation methods : Lecture : Bibliographic assay (50%) + Projet Report (50%)